"From the crown to the toe, top-full of direst cruelty"

When Lady Macbeth reads the letter from Macbeth she's told how Macbeth was addressed as the Thane of Cawdor. She knows it will happen but she fears that he's too loyal, honorable and noble to overthrow King Duncan. So when she finds out that King Duncan is coming she wants all traces of kindness, compassion, remorse, and womanly feeling taken out so that she can be ruthless and kill King Duncan and not feel regret to help her husband be king and become greater. I thought during Shakespeare's time this would've been completely different from how woman are looked upon because they would've been viewed as kind and weak beings but she wants to become a ruthless cold-hearted killer willing to remove her feminine traits to help her husband become king, in the process changing her. She wanted to change so no feelings of compassion or pity could stop her from killing the king. In her whole speech she wants to attain a level of cruelty to kill that not even a higher being can tell her to stop.